Resume/CV
Education
PhD - University of Cambridge (2016-2021)
MSc in biomedical engineering, neurotechnology stream - Imperial College (2012-2013)
BEng in life sciences and engineering - EPFL (2009-2012)
Experience
Postdoctoral fellow - the Francis Crick Institute (2021-present)
Biomedical insights consultant - Lifebit (2019)
Vice-president - Innovation forum Cambridge (2018-2019)
IMAGINE IF! accelerator co-ordinator (2018-2019)
Research assistant - University of Cambridge (2016-2016)
Visiting scholar - Broad Institute of Harvard and MIT (2014-2015)
Publications
Arturo Casini, James T MacDonald, Joachim De Jonghe, Georgia Christodoulou, Paul S Freemont, Geoff S Baldwin, Tom Ellis. One-pot DNA construction for synthetic biology: the Modular Overlap-Directed As- sembly with Linkers (MODAL) strategy. Nucleic acids research, 2014/10/1
Benjamin Reeve, Elena Martinez Klimova, Joachim De Jonghe, David J Leak, Tom Ellis. The Geobacillus plasmid set: a modular toolkit for thermophile engineering. ACS Synthetic Biology, 2016/7/1
Soohong Kim, Joachim De Jonghe, Anthony B Kulesa, David Feldman, Tommi Vatanen, Roby P Bhattacharyya, Brittany Berdy, James Gomez, Jill Nolan, Slava Epstein, Paul C Blainey. High-throughput automated microfluidic sample preparation for accurate microbial genomics. Nature Communications, 2017/1/27
Berna Sozen*, Andy L Cox*, Joachim De Jonghe*, Min Bao, Florian Hollfelder, David M Glover, Magdalena Zernicka-Goetz. Self-organization of mouse stem cells into an extended potential blastoid. Developmental Cell, 2019/12/19. * equal contribution
Gianluca Amadei, Kasey YC Lau, Joachim De Jonghe, Carlos W Gantner, Berna Sozen, Christopher Chan, Meng Zhu, Christos Kyprianou, Florian Hollfelder, Magdalena Zernicka-Goetz. Inducible stem-cell-derived embryos capture mouse morphogenetic events in vitro. Developmental Cell, 2021/2/8
Fredrik Salmen*, Joachim De Jonghe*, Tomasz Kaminski, Anna Alemany, Guillermo Parada, Ayaka Yanagida, Timo N Kohler, Nicolas Battich, Floris van den Brekel, Anna L Ellermann, Alfonso Martinez Arias, Jennifer Nichols, Martin Hemberg, Florian Hollfelder, Alexander van Oudenaarden. High-throughput total RNA sequencing in single cells using VASA-seq. Nature Biotechnology, 2022/06/28. * equal contribution
Gianluca Amadei*, Charlotte E Handford*, Chengxiang Qiu, Joachim De Jonghe, Hannah Greenfeld, Martin Tran, Beth K Martin, Dong-Yuan Chen, Alejandro Aguilera-Castrejon, Jacob H Hanna, Michael Elowitz, Florian Hollfelder, Jay Shendure, David M Glover, Magdalena Zernicka-Goetz. Embryo models complete gastrulation to neurulation and organogenesis. Nature, 2022/08/125. * equal contribution
Min Bao, Jake Cornwall-Scoones, Estefania Sanchez-Vasquez, Dong-Yuan Chen, Joachim De Jonghe, Shahriar Shadkhoo, Florian Hollfelder, Matt Thomson, David M Glover, Magdalena Zernicka-Goetz. Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension. Nature Cell Biology, 2022/09/14.
Timo N Kohler*, Joachim De Jonghe*, Anna L Ellermann*, Ayaka Yanagida, Michael Herger, Erin M Slatery, Antonia Weberling, Clara Munger, Katrin Fischer, Carla Mulas, Alex Winkel, Connor Ross, Sophie Bergmann, Kristian Franze, Kevin Chalut, Jennifer Nichols, Thorsten E Boroviak, Florian Hollfelder. Plakoglobin is a mechanosensitive regulator of naive pluripotency. Nature Communications, 2023/07/07.
Joachim De Jonghe*, Tomasz S Kaminski*, David B Morse, Marcin Tabaka, Anna L Ellermann, Timo N Kohler, Gianluca Amadei, Charlotte E Handford, Gregory M Findlay, Magdalena Zernicka-Goetz, Sarah A Teichmann, Florian Hollfelder. spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content. Nature Communications, 2023/08/08.
Patents
Modular microfluidic methods and devices
Modular microfluidic devices, methods and systems for total RNA analysis
Doctoral thesis
My doctoral thesis is currently embargoed for public access
Certificates
Fundamentals of deep learning - NVIDIA Deep Learning Institute (2022/06)
IELTS - C1 level (2016/04)
Honors and awards
Postdoctoral fellowship, Kuok fellowship - The Francis Crick Institute (2021-2022)
Departmental prize - best poster (2018)
BBSRC DTP doctoral scholarship (2016)
First class honours (distinction) - MSc in biomedical engineering - Imperial College London (2013)