Resume/CV

Education

PhD - University of Cambridge (2016-2021)

MSc in biomedical engineering, neurotechnology stream - Imperial College (2012-2013)

BEng in life sciences and engineering - EPFL (2009-2012)

Experience

Postdoctoral fellow - the Francis Crick Institute (2021-present)

Biomedical insights consultant - Lifebit (2019)

Vice-president - Innovation forum Cambridge (2018-2019)

IMAGINE IF! accelerator co-ordinator (2018-2019)

Research assistant - University of Cambridge (2016-2016)

Visiting scholar - Broad Institute of Harvard and MIT (2014-2015)

Publications

Arturo Casini, James T MacDonald, Joachim De Jonghe, Georgia Christodoulou, Paul S Freemont, Geoff S Baldwin, Tom Ellis. One-pot DNA construction for synthetic biology: the Modular Overlap-Directed As- sembly with Linkers (MODAL) strategy. Nucleic acids research, 2014/10/1  

Benjamin Reeve, Elena Martinez Klimova, Joachim De Jonghe, David J Leak, Tom Ellis. The Geobacillus plasmid set: a modular toolkit for thermophile engineering. ACS Synthetic Biology, 2016/7/1

Soohong Kim, Joachim De Jonghe, Anthony B Kulesa, David Feldman, Tommi Vatanen, Roby P Bhattacharyya, Brittany Berdy, James Gomez, Jill Nolan, Slava Epstein, Paul C Blainey. High-throughput automated microfluidic sample preparation for accurate microbial genomics. Nature Communications, 2017/1/27

Berna Sozen*, Andy L Cox*, Joachim De Jonghe*, Min Bao, Florian Hollfelder, David M Glover, Magdalena Zernicka-Goetz. Self-organization of mouse stem cells into an extended potential blastoid. Developmental Cell, 2019/12/19.                       * equal contribution

Gianluca Amadei, Kasey YC Lau, Joachim De Jonghe, Carlos W Gantner, Berna Sozen, Christopher Chan, Meng Zhu, Christos Kyprianou, Florian Hollfelder, Magdalena Zernicka-Goetz. Inducible stem-cell-derived embryos capture mouse morphogenetic events in vitro. Developmental Cell, 2021/2/8

Fredrik Salmen*, Joachim De Jonghe*, Tomasz Kaminski, Anna Alemany, Guillermo Parada, Ayaka Yanagida, Timo N Kohler, Nicolas Battich, Floris van den Brekel, Anna L Ellermann, Alfonso Martinez Arias, Jennifer Nichols, Martin Hemberg, Florian Hollfelder, Alexander van Oudenaarden. High-throughput total RNA sequencing in single cells using VASA-seq. Nature Biotechnology, 2022/06/28.      * equal contribution

Gianluca Amadei*, Charlotte E Handford*, Chengxiang Qiu, Joachim De Jonghe, Hannah Greenfeld, Martin Tran, Beth K Martin, Dong-Yuan Chen, Alejandro Aguilera-Castrejon, Jacob H Hanna, Michael Elowitz, Florian Hollfelder, Jay Shendure, David M Glover, Magdalena Zernicka-Goetz. Embryo models complete gastrulation to neurulation and organogenesis.  Nature, 2022/08/125.                       * equal contribution

Min Bao, Jake Cornwall-Scoones, Estefania Sanchez-Vasquez, Dong-Yuan Chen, Joachim De Jonghe, Shahriar Shadkhoo, Florian Hollfelder, Matt Thomson, David M Glover, Magdalena Zernicka-Goetz. Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension. Nature Cell Biology, 2022/09/14.


Timo N Kohler*, Joachim De Jonghe*, Anna L Ellermann*, Ayaka Yanagida, Michael Herger, Erin M Slatery, Antonia Weberling, Clara Munger, Katrin Fischer, Carla Mulas, Alex Winkel, Connor Ross, Sophie Bergmann, Kristian Franze, Kevin Chalut, Jennifer Nichols, Thorsten E Boroviak, Florian Hollfelder. Plakoglobin is a mechanosensitive regulator of naive pluripotency. Nature Communications, 2023/07/07.


Joachim De Jonghe*, Tomasz S Kaminski*, David B Morse, Marcin Tabaka, Anna L Ellermann, Timo N Kohler, Gianluca Amadei, Charlotte E Handford, Gregory M Findlay, Magdalena Zernicka-Goetz, Sarah A Teichmann, Florian Hollfelder. spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content. Nature Communications, 2023/08/08.


Patents

Doctoral thesis

High-throughput barcoding technologies to dissect mouse embryonic development at the single-cell level. 2021/8/9

My doctoral thesis is currently embargoed for public access

Certificates

Fundamentals of deep learning - NVIDIA Deep Learning Institute (2022/06)

IELTS - C1 level (2016/04)

Honors and awards

Postdoctoral fellowship,  Kuok fellowship - The Francis Crick Institute (2021-2022)

Departmental prize - best poster (2018)

BBSRC DTP doctoral scholarship (2016)

First class honours (distinction) - MSc in biomedical engineering - Imperial College London (2013)